College Football Picks Ohio State vs Penn State Betting Odds & Predictions:The Ohio State Buckeyes will head into their week 10 college football picks matchup against the Penn State Nittany Lions with two consecutive wins. After  dominating New Mexico State last week 45-0, the Buckeyes will face a Nittany Lions team that has won five consecutive college football picks matchups. According to the college football odds makers from the internet's top online sportsbooks this week 10 college football picks betting line has moved over two points since they were originally posted early this week. The college football odds makers currently list the Buckeyes as the +5½(-110) point college football picks underdog vs the Nittany Lions who are set as the -5½(-110) point college football picks favorite. If your an online sports handicapper and planning to make your college football selections on the game total the college football odds makers at BetUS.com have posted the total to 41( ov-110).

Coming of a 34-13 victory over the Northwestern Wildcats, the home field favorite Nittany Lions will need to keep the Buckeyes offense in check after they demonstrated against a weak New Mexico State defense that they can rack-up the yardage. The Ohio State Buckeyes earned 559 total yards against New Mexico State in last weeks college football picks matchup, QB Terrelle Prior earned 135 yards going 11/23 and a touchdown pass to Dane Sanzenbacher. The Ohiop State Buckeyes rushing game was the driving force on the Buckeyes win over New Mexico State with TD's from Terrelle Pryor, Brandon Saine and Daniel Herron.

The Ohio State Buckeyes dominated in last weeks college football picks matchup, however this week the Buckeyes will surely get a bigger test than what New Mexico State brought to the table. The No 11 Penn State Nittany Lions are coming off a 34-13 college football picks win at Ryan FieldwherePenn State exploded in the fourth quarter to end the 13-13 tie that carried through the third quarter.

Here are a few football prediction trends to consider before you make your college football predictions on the Ohio State vs Penn State matchup:

• Penn State are 15-6-1 in their last 22 games as a favorite
• Penn State are 8-3 in their last 11 home games as a favorite
• Penn State are 10-4 in their last 14 home games as a favorite
• Ohio State Under is 5-1 in OHIOST last 6 road games
• The Total has gone Under in 5-1 in OHIOST last 6 road games as an underdog
• The Total has gone Over in 3-8 in OHIOST last 11 road games
• Penn State Under is 4-1-1 in PENNST last 6 games as a favorite
• Penn State Over is 2-5-1 in PENNST last 8 games as a favorite
• Penn State Over is 4-10 in PENNST last 14 home games as a favorite

OnlineSportsHandicappers.com College Football Picks Ohio State vs Penn State Betting Odds & Predictions

Will Penn State explode once again or will the Ohio State buckeyes step to win over a more formidable opponent? Find the best college football odds and betting odds for this Ohio State vs Penn State and all the week 10 college football picks matchups. The College football odds makers at BetUS.com are giving online sports handicappers a FREE $200 Signup Bonus when they deposit and wager on Ohio State vs Penn State or any week 10 college football picks matchup.

How are you going to call it?